This paper contributes a new technique for the estimation of structure in continuous time Bayesian networks, and completes the picture with an accompanying inference method and an illustration on a real-world problem. There is agreement among reviewers that this is a high quality contribution, if one takes the confidence-weighted scores from reviewers into account. As a point for improvement for the paper, we could reiterate a comment that was raised in the reviewer discussion: "[the paper] is missing reasonable and helpful experimental comparisons that are not hard to do, given that the code exists already in CTBN-RLE" and the authors are encouraged to consider broadening their experimental comparisons for a final published version.