Dynamic Modulation of Neurons and Networks

Part of Advances in Neural Information Processing Systems 6 (NIPS 1993)

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Eve Marder


Biological neurons have a variety of intrinsic properties because of the large number of voltage dependent currents that control their activity. Neuromodulatory substances modify both the balance of conductances that determine intrinsic properties and the strength of synapses. These mechanisms alter circuit dynamics, and suggest that functional circuits exist only in the modulatory environment in which they operate.